{"id":2621,"date":"2023-07-21T05:27:57","date_gmt":"2023-07-21T05:27:57","guid":{"rendered":"https:\/\/www.floridarehab.com\/?page_id=2621"},"modified":"2025-02-07T12:16:53","modified_gmt":"2025-02-07T12:16:53","slug":"what-is-wernicke-korsakoff-syndrome","status":"publish","type":"blog","link":"https:\/\/www.floridarehab.com\/alcohol\/what-is-wernicke-korsakoff-syndrome\/","title":{"rendered":"What Is Wernicke-Korsakoff Syndrome (Wet Brain)?"},"content":{"rendered":"\n<p class=\"eplus-wrapper wp-block-paragraph\">Wernicke-Korsakoff Syndrome is caused by malnutrition when someone does not get enough thiamin in their diet. A leading cause is alcoholism.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Wernicke-Korsakoff Syndrome (WKS) is a condition that happens when someone is deficient in&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28351256\" target=\"_blank\" rel=\"noreferrer noopener\">vitamin B1<\/a>&nbsp;(thiamin). Thiamin is critical for the functioning of brain cells because it helps them to produce energy. WKS is a combination of two different conditions: Wernicke\u2019s encephalopathy and Korsakoff syndrome.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">The condition is most common in people with severe malnutrition associated with&nbsp;<a href=\"https:\/\/www.floridarehab.com\/alcohol\/addiction\/\">alcoholism<\/a>, AIDS and gastrointestinal disorders.<\/p>\n\n\n\n<h3 class=\" wp-block-heading eplus-wrapper\">Why Is It Also Called Wet Brain?<\/h3>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">WKS is called \u201cwet brain syndrome\u201d because the condition is common in people who abuse alcohol.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\"><a href=\"https:\/\/www.floridarehab.com\/treatment\/medical-detox\/diet-guide\/\">Alcoholics are deficient in thiamin<\/a>&nbsp;for a couple of different reasons. The first is that they tend to have poor diets without much nutritional value. They may favor easy, cheap and fatty meals that are low in thiamin and other B vitamins.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">The second reason is that even if alcoholics have a well-rounded diet, alcohol changes the functioning of cells in the intestines. Intestinal cells have proteins on their surface whose job it is to absorb thiamin.&nbsp;<a href=\"https:\/\/www.floridarehab.com\/alcohol\/\">Alcohol<\/a>&nbsp;causes cells of the gut to make less of this protein. So even if they eat a diet high in thiamin, it may not absorb properly, leading to WKS.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Since WKS is two different conditions that happen together, it is helpful to understand each separately.<\/p>\n\n\n\n<h4 class=\" wp-block-heading eplus-wrapper\">Wernicke\u2019s Encephalopathy (WE)<\/h4>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Thiamin deficiency causes Wernicke\u2019s encephalopathy. It is a medical emergency, and the earlier it is recognized, the better the outcome will be. Symptoms may be hard to distinguish from alcohol intoxication, but they can show up even when someone is sober or experiencing&nbsp;<a href=\"https:\/\/www.floridarehab.com\/alcohol\/withdrawal-detox\/\">alcohol withdrawal<\/a>. Key symptoms include confusion, loss of muscle coordination (they may suddenly have trouble walking) and abnormal eye movements.<\/p>\n\n\n\n<h4 class=\" wp-block-heading eplus-wrapper\">Korsakoff Syndrome (KS)<\/h4>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Also known as Korsakoff psychosis, this syndrome develops as WE subsides. KS is the result of permanent brain damage from thiamin deficiency, and symptoms remain long-term. Even if WE is caught early and treated, symptoms of Korsakoff Syndrome may still develop.<\/p>\n\n\n\n<h2 class=\" wp-block-heading eplus-wrapper\">Alcohol Abuse &amp; Wernicke-Korsakoff Syndrome<\/h2>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">While WKS can manifest in anyone with severe malnutrition, alcoholics are especially susceptible. If WKS is not caught and treated, symptoms may worsen and eventually lead to death. The conditions can be slowed and stopped with treatment, but some symptoms of Korsakoff Syndrome may be permanent.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">To help prevent WKS, a prevent who abuses alcohol may take thiamin <a href=\"https:\/\/www.floridarehab.com\/alcohol\/withdrawal-detox\/vitamins\/\">supplements<\/a>, but this not does completely erase the risk. Alcohol directly inhibits the absorption of thiamin in the gut, so even if an alcoholic diligently takes thiamin supplements, it may not absorb properly.<\/p>\n\n\n\n\n\n<h2 class=\" wp-block-heading eplus-wrapper\">Symptoms Of Wernicke-Korsakoff Syndrome<\/h2>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Wernicke\u2019s encephalopathy has three key symptoms.&nbsp;<a href=\"https:\/\/medlineplus.gov\/ency\/article\/000771.htm\" target=\"_blank\" rel=\"noreferrer noopener\">The symptoms are<\/a>:<\/p>\n\n\n\n<ul class=\" wp-block-list eplus-wrapper\">\n<li class=\" eplus-wrapper\">Abnormal eye movements like nystagmus (back and forth movements), double vision or eyelid drooping <\/li>\n\n\n\n<li class=\" eplus-wrapper\">Ataxia, or lack of voluntary muscle coordination <\/li>\n\n\n\n<li class=\" eplus-wrapper\">Confusion and loss of mental activity<\/li>\n<\/ul>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Korsakoff\u2019s syndrome shows up after the symptoms of WE go away. KS is permanent, and its symptoms range in severity based on each individual. Some examples of symptoms may include:<\/p>\n\n\n\n<ul class=\" wp-block-list eplus-wrapper\">\n<li class=\" eplus-wrapper\">Confabulation (making up stories) <\/li>\n\n\n\n<li class=\" eplus-wrapper\">Hallucinations (seeing or hearing things that are not there) <\/li>\n\n\n\n<li class=\" eplus-wrapper\">Memory loss <\/li>\n\n\n\n<li class=\" eplus-wrapper\">Problems forming new memories<\/li>\n<\/ul>\n\n\n\n\n\n<h2 class=\" wp-block-heading eplus-wrapper\">Wernicke-Korsakoff Syndrome Treatment<\/h2>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">WKS is treated with thiamin supplementation in the hospital. Thiamin can be given by mouth or as an injection in the muscle (intramuscular) or vein (intravascular). Since alcoholics may not absorb thiamin taken orally, most of the time they receive an injection.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">The only guaranteed method to prevent WKS is to maintain a healthy diet, which in this case means quitting alcohol or reducing consumption.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\"><strong>If you or a loved one is drinking heavily over long periods, your risk of developing WKS is higher than normal. WKS is preventable, and the best way to prevent it is to stop drinking alcohol. If you need help drinking less or quitting entirely, please call&nbsp;<a href=\"https:\/\/www.floridarehab.com\/contact-us\/\">The Recovery Village Palm Beach at Baptist Health<\/a>&nbsp;to explore treatment options and to receive the help you deserve.<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Wernicke-Korsakoff Syndrome is caused by malnutrition when someone does not get enough thiamin in their diet. A leading cause is alcoholism. Wernicke-Korsakoff Syndrome (WKS) is a condition that happens when someone is deficient in&nbsp;vitamin B1&nbsp;(thiamin). Thiamin is critical for the functioning of brain cells because it helps them to produce energy. WKS is a combination [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":11579,"parent":697,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false},"categories":[16],"tags":[],"class_list":["post-2621","blog","type-blog","status-publish","has-post-thumbnail","hentry","category-alcohol"],"acf":{"written_by":319,"enable_medically_and_up":["Yes"],"medically_reviewed_by":269,"medically_reviewed_content":"This article was reviewed by a medical professional to guarantee the delivery of accurate and up-to- date information. <a href=\"\/research\/\">View our research policy.<\/a>","up_to_date":"Medically Reviewed by <a href=\"\/team\/editorial\/dr-conor-sheehy-pharmd-bcps-cacp\/\">Conor Sheehy, PharmD, BCPS, CACP<\/a>","page_first_published_date":"20220104","page_last_edit_date":"20220104","highlighted_description":"If you or a loved one is struggling with addiction, help is available. Speak with a Recovery Advocate by calling <a href=\"tel:8886480738\" ><b>888-648-0738<\/b><\/a> now.","key_takeaways":"","source":{"source_label":"View Sources","source_content":"Medline Plus. <a href=\"https:\/\/medlineplus.gov\/ency\/article\/000771.htm\" target=\"_blank\" rel=\"noopener\">\u201cWernicke-Korsakoff Syndrome.\u201d<\/a> 2016. Accessed October 4, 2019.\r\n\r\nDonnelly, Alexander. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28351256\" target=\"_blank\" rel=\"noopener\">\u201cWernicke-Korsakoff Syndrome: Recognition and Treatment.\u201d<\/a> Nursing Standard, 2017. Accessed October 4, 2019."},"staff_member_heading":"Authorship","staff_member":[{"staff_member_title":"Editor","select_staff_member":319},{"staff_member_title":"Medical Reviewer","select_staff_member":269}],"insurance_label":""},"_links":{"self":[{"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/blog\/2621","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/blog"}],"about":[{"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/types\/blog"}],"author":[{"embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/comments?post=2621"}],"version-history":[{"count":0,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/blog\/2621\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/blog\/697"}],"acf:post":[{"embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/staff\/269"},{"embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/staff\/319"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/media\/11579"}],"wp:attachment":[{"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/media?parent=2621"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/categories?post=2621"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/tags?post=2621"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}