{"id":3493,"date":"2023-07-27T06:11:31","date_gmt":"2023-07-27T06:11:31","guid":{"rendered":"https:\/\/www.floridarehab.com\/?page_id=3493"},"modified":"2025-03-13T21:05:40","modified_gmt":"2025-03-13T21:05:40","slug":"withdrawal-timeline","status":"publish","type":"blog","link":"https:\/\/www.floridarehab.com\/drugs\/hydrocodone-addiction\/withdrawal-timeline\/","title":{"rendered":"Hydrocodone Withdrawal Timeline, Symptoms &amp; Detox"},"content":{"rendered":"\n<p class=\"eplus-wrapper wp-block-paragraph\"><a href=\"https:\/\/www.floridarehab.com\/drugs\/hydrocodone\/addiction\/\">Hydrocodone<\/a> is one of the <a href=\"https:\/\/www.deadiversion.usdoj.gov\/drug_chem_info\/hydrocodone.pdf\" target=\"_blank\" rel=\"noopener\">most prescribed<\/a> and <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fphar.2018.01122\/full\" target=\"_blank\" rel=\"noopener\">most abused<\/a> opioids in the United States. Nearly all the world\u2019s hydrocodone is <a href=\"https:\/\/www.incb.org\/documents\/Publications\/AnnualReports\/AR2022\/Annual_Report\/E_INCB_2022_1_eng.pdf\" target=\"_blank\" rel=\"noopener\">used<\/a> in the United States, and more than 30 million prescriptions involving hydrocodone were <a href=\"https:\/\/clincalc.com\/DrugStats\/Drugs\/AcetaminophenHydrocodone\" target=\"_blank\" rel=\"noopener\">dispensed<\/a> in 2020 alone.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Hydrocodone is available on its own as a long-acting tablet both as a generic drug and under the brand name Hysingla ER. It is also available as a generic long-acting tablet that was previously sold under the brand name Zohydro ER.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Hydrocodone is also available in its short-acting form as a combination medication with acetaminophen, the active ingredient in Tylenol. Although hydrocodone\/acetaminophen tabs are currently only sold as generic drugs, they were previously available under brand names like Lorcet, Lortab, Norco and Vicodin.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">People ready to stop their hydrocodone use must first pass through hydrocodone withdrawal as their body undergoes detox. Understanding how hydrocodone withdrawal and detox works can benefit people taking their first step toward long-term sobriety during this crucial process.<\/p>\n\n\n\n<h2 class=\" wp-block-heading eplus-wrapper\"><strong>Hydrocodone Withdrawal Symptoms<\/strong><\/h2>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">When you take hydrocodone on a regular basis, the brain adapts to its presence. Suddenly stopping the drug can trigger extremely uncomfortable withdrawal symptoms as the brain struggles to adapt. Hydrocodone withdrawal symptoms are similar to <a href=\"https:\/\/www.floridarehab.com\/drugs\/opioids\/withdrawal-detox\/\">withdrawal from other opioids<\/a>. Withdrawal symptoms involve physical and psychological aspects, <a href=\"https:\/\/sitefinitystorage.blob.core.windows.net\/sitefinity-production-blobs\/docs\/default-source\/guidelines\/npg-jam-supplement.pdf?sfvrsn=a00a52c2_2\" target=\"_blank\" rel=\"noopener\">including<\/a>:<\/p>\n\n\n\n<ul class=\"eplus-wrapper wp-block-list\">\n<li class=\" eplus-wrapper\">Muscle aches&nbsp;<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Insomnia<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Runny nose<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Runny eyes<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Sweating<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Goosebumps<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Yawning<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Cravings<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Enlarged pupils<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Abdominal cramps<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Diarrhea<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Nausea and vomiting<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Agitation<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Anxiety<\/li>\n<\/ul>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">These symptoms can be difficult to overcome without support. Those who struggle through withdrawal on their own without medical help have a <a href=\"https:\/\/sitefinitystorage.blob.core.windows.net\/sitefinity-production-blobs\/docs\/default-source\/guidelines\/npg-jam-supplement.pdf?sfvrsn=a00a52c2_2\" target=\"_blank\" rel=\"noopener\">higher<\/a> rate of relapse as their bodies rebel against the drug\u2019s sudden absence. For these reasons, those who want to quit hydrocodone should do so with medical help from their doctor, preferably in a medical detox setting.<\/p>\n\n\n\n<h2 class=\" wp-block-heading eplus-wrapper\"><strong>Hydrocodone Withdrawal Timeline<\/strong><\/h2>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Although everyone has a unique hydrocodone withdrawal experience, the withdrawal itself tends to follow a timeline. However, the timeline can differ depending on whether you take short-acting hydrocodone (Vicodin) or long-acting hydrocodone (Hysingla ER). It is important to remember that any withdrawal symptom can occur at any time during the withdrawal process.&nbsp;<\/p>\n\n\n\n<h3 class=\" wp-block-heading eplus-wrapper\">12 Hours to 30 Hours After the Last Dose: Symptom onset<\/h3>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Hydrocodone has an elimination half-life of <a href=\"https:\/\/www.drugs.com\/monograph\/hydrocodone.html\" target=\"_blank\" rel=\"noopener\">around<\/a> four hours for the short-acting version and up to nine hours for the long-acting version. The half-life of a drug is the time it takes the body to metabolize and excrete one-half of that drug. Withdrawal symptoms usually <a href=\"https:\/\/sitefinitystorage.blob.core.windows.net\/sitefinity-production-blobs\/docs\/default-source\/guidelines\/npg-jam-supplement.pdf?sfvrsn=a00a52c2_2\" target=\"_blank\" rel=\"noopener\">develop<\/a> after more than one half-life has passed. Generally, this means that symptoms develop within 12 hours for the short-acting versions and within 30 hours for the long-acting versions.<\/p>\n\n\n\n<h3 class=\" wp-block-heading eplus-wrapper\">24\u201348 Hours to 3\u20138 Days After the Last Dose: Symptoms Peak<\/h3>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">After hydrocodone has completely left your body, your brain must learn to adapt to the drug\u2019s absence. This can take a few days and can lead to worsened withdrawal symptoms as your brain tries to recalibrate. These symptoms <a href=\"https:\/\/sitefinitystorage.blob.core.windows.net\/sitefinity-production-blobs\/docs\/default-source\/guidelines\/npg-jam-supplement.pdf?sfvrsn=a00a52c2_2\" target=\"_blank\" rel=\"noopener\">tend<\/a> to peak between 24 and 48 hours after the last dose of short-acting hydrocodone and between three and eight days after the last dose of long-acting hydrocodone.&nbsp;<\/p>\n\n\n\n<h3 class=\" wp-block-heading eplus-wrapper\">3\u20135 Days to 10 Days After the Last Dose: Symptoms Ease<\/h3>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Withdrawal symptoms start to resolve after a few days, as your brain gets used to being without hydrocodone. This <a href=\"https:\/\/sitefinitystorage.blob.core.windows.net\/sitefinity-production-blobs\/docs\/default-source\/guidelines\/npg-jam-supplement.pdf?sfvrsn=a00a52c2_2\" target=\"_blank\" rel=\"noopener\">can take<\/a> three to five days after the last dose of short-acting hydrocodone and 10 days after the last dose of long-acting hydrocodone. Although symptoms get better during this period of time, the underlying addiction itself still needs to be treated. Experts <a href=\"https:\/\/sitefinitystorage.blob.core.windows.net\/sitefinity-production-blobs\/docs\/default-source\/guidelines\/npg-jam-supplement.pdf?sfvrsn=a00a52c2_2\" target=\"_blank\" rel=\"noopener\">recommend<\/a> at least 90 days of rehab to help keep you off hydrocodone for good.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Some people may develop symptoms that last beyond the acute withdrawal phase. These symptoms are known as protracted withdrawal symptoms and may last for weeks or months. These lingering symptoms tend to <a href=\"https:\/\/store.samhsa.gov\/sites\/default\/files\/d7\/priv\/sma10-4554.pdf\" target=\"_blank\" rel=\"noopener\">include<\/a> anxiety, depression and insomnia.<\/p>\n\n\n\n<h3 class=\" wp-block-heading eplus-wrapper\"><strong>Factors Impacting Hydrocodone Withdrawal<\/strong><\/h3>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Multiple factors can impact the duration of hydrocodone withdrawal. Some people metabolize hydrocodone <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fphar.2018.01122\/full\" target=\"_blank\" rel=\"noopener\">particularly slowly<\/a> (for genetic reasons), so the onset and duration of withdrawal symptoms may take longer for them. The severity and duration of symptoms of hydrocodone withdrawal will also depend on the history of hydrocodone use (length and frequency of use and dose taken) and specific individual characteristics such as metabolic rate. Hydrocodone abuse is often accompanied by the co-use of alcohol and other substances. Such polydrug use can result in more severe withdrawal symptoms that may involve complications.&nbsp;<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">A co-occurring disorder like depression or anxiety can also prolong and complicate the recovery process if left untreated. For this reason, The Recovery Village offers a dual diagnosis rehab option to treat any underlying mental health problems concurrently with your addiction.<\/p>\n\n\n\n<h2 class=\" wp-block-heading eplus-wrapper\"><strong>How To Cope With Hydrocodone Withdrawal<\/strong><\/h2>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Although the symptoms of hydrocodone withdrawal are not life-threatening, they can be extremely uncomfortable. These symptoms resemble that of a bad flu and can cause a relapse. For this reason, a medically supervised detox is important to help you gently wean from hydrocodone, followed by rehab. Treatment at an <a href=\"https:\/\/www.floridarehab.com\/treatment\/inpatient-rehab\/\">inpatient medical detox<\/a> in a drug-free environment can reduce the chances of a relapse.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">The use of hydrocodone should not be abruptly discontinued, as this can result in severe withdrawal symptoms. Instead, the dose of hydrocodone should be gradually reduced or tapered. This involves following a taper schedule whereby the dose of hydrocodone is reduced by a specific amount at predefined intervals. The taper schedule adopted may depend on the severity of dependence and the psychological and metabolic characteristics of the individual.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Another alternative is the use of opioid replacement therapy. Opioid replacement therapy involves the use of medications like <a href=\"https:\/\/www.floridarehab.com\/treatment\/medication-assisted-treatment\/methadone\/\">methadone<\/a> or <a href=\"https:\/\/www.floridarehab.com\/treatment\/medication-assisted-treatment\/buprenorphine\/\">buprenorphine<\/a>. These drugs also bind to opioid receptors but do not produce the same effects as hydrocodone due to their gradual mode of action. These drugs can help reduce the symptoms of hydrocodone withdrawal.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Medications like <a href=\"https:\/\/www.floridarehab.com\/treatment\/medication-assisted-treatment\/clonidine\/\">clonidine<\/a> and lofexidine that reduce blood pressure can help alleviate some withdrawal symptoms such as insomnia, diarrhea, nausea, <a href=\"https:\/\/www.floridarehab.com\/co-occurring-disorders\/anxiety-disorders\/\">anxiety<\/a> and tremors. Other medications may also be used to treat specific symptoms that arise during <a href=\"https:\/\/www.floridarehab.com\/drugs\/hydrocodone\/related\/withdrawal-timeline\/\">hydrocodone withdrawal<\/a>. These include loperamide to treat diarrhea and vomiting and non-steroidal anti-inflammatory drugs for muscle pain.<\/p>\n\n\n\n<h2 class=\" wp-block-heading eplus-wrapper\"><strong>Hydrocodone Detox<\/strong><\/h2>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Hydrocodone is a psychoactive drug, meaning that it changes the brain\u2019s chemistry and disrupts its normal functioning. The brain tries to compensate for the drug\u2019s disruptive effects, making adjustments and attempting to function normally despite the drug\u2019s presence.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">When the drug use stops or drastically reduces, the brain must adjust. If the brain is forced to do so abruptly (i.e., without a taper), this causes withdrawal symptoms.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">The process of hydrocodone detox can be an uncomfortable experience. Fortunately, this process can be medically assisted to minimize the impact on the brain and body to reduce or eliminate the discomfort.<\/p>\n\n\n\n<h3 class=\" wp-block-heading eplus-wrapper\">How Long Does It Take To Detox From Hydrocodone?<\/h3>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">As mentioned, the process depends on individual factors, but generally, it <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK554498\/\" target=\"_blank\" rel=\"noopener\">takes<\/a> five half-lives for the drug to be completely eliminated from the body. However, the withdrawal symptoms and detox process can continue well beyond that range\u2014possibly <a href=\"https:\/\/sitefinitystorage.blob.core.windows.net\/sitefinity-production-blobs\/docs\/default-source\/guidelines\/npg-jam-supplement.pdf?sfvrsn=a00a52c2_2\" target=\"_blank\" rel=\"noopener\">lasting<\/a> for up to five days for short-acting hydrocodone and up to 10 days for long-acting hydrocodone.<\/p>\n\n\n\n<h4 class=\" wp-block-heading eplus-wrapper\">Detoxing at Home<\/h4>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">When making the decision to attempt hydrocodone detox at home, individuals should do so in conjunction with their physician or an addiction professional and should be clear about the extent of their drug use. People attempting at-home detox should also involve loved ones in the process and ensure they\u2019re aware of signs indicative of a medical emergency.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">People tend to overestimate their ability to stop their drug use on their own, even if they failed attempts to do so in the past. Detoxing from hydrocodone at home may not provide the best opportunity for success, as the hydrocodone cravings may be overwhelming.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">At the minimum, people who plan to detox at home should have certain supporting factors in place:<\/p>\n\n\n\n<ul class=\"eplus-wrapper wp-block-list\">\n<li class=\" eplus-wrapper\">Consultation with and agreement from their doctor<\/li>\n\n\n\n<li class=\" eplus-wrapper\">A short period of drug use at lower doses&nbsp;<\/li>\n\n\n\n<li class=\" eplus-wrapper\">A stable and supportive home environment&nbsp;<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Not living alone and the people at home made aware of the detox situation<\/li>\n\n\n\n<li class=\" eplus-wrapper\">A high motivation to recover&nbsp;<\/li>\n\n\n\n<li class=\" eplus-wrapper\">A safe, drug-free home away from negative influences such as dealers or drug users&nbsp;<\/li>\n\n\n\n<li class=\" eplus-wrapper\">A set plan of action for treatment and recovery after detoxing<\/li>\n<\/ul>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">It should be noted that detox does not constitute treatment for hydrocodone addiction. Recovery from drug use takes much more than simply abstaining from drug use. A return to good health and lasting recovery requires addressing the reasons behind the substance use, whatever they might be. This requirement is the main purpose of <a href=\"https:\/\/www.floridarehab.com\/treatment\/\">addiction treatment programs<\/a>.<\/p>\n\n\n\n<h4 class=\" wp-block-heading eplus-wrapper\">Medically Assisted Detox<\/h4>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\"><a href=\"https:\/\/www.floridarehab.com\/treatment\/medical-detox\/\">Medically assisted detox<\/a> is the use of proper medical support and supervision\u2014with or without the use of supportive medications\u2014to help people get through detox and withdrawal safely, comfortably and with minimal shock to their bodies.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Medically assisted detox provides the option of using <a href=\"https:\/\/www.floridarehab.com\/treatment\/medication-assisted-treatment\/\">opioid replacement therapy<\/a> to prevent or reduce withdrawal. It also provides:<\/p>\n\n\n\n<ul class=\"eplus-wrapper wp-block-list\">\n<li class=\" eplus-wrapper\">A safe place to detox away from distractions, temptations and triggers<strong>&nbsp;<\/strong><\/li>\n\n\n\n<li class=\" eplus-wrapper\">Immediate help if any complications arise<strong>&nbsp;<\/strong><\/li>\n\n\n\n<li class=\" eplus-wrapper\">Proper non-opioid management of side effects, such as insomnia, low mood or diarrhea&nbsp;<\/li>\n\n\n\n<li class=\" eplus-wrapper\">The ability to connect with other motivated people who are detoxing&nbsp;<\/li>\n\n\n\n<li class=\" eplus-wrapper\">The ability to connect with counselors and begin working out an individualized plan of success for long-term recovery&nbsp;<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Access to proper information and facts straight from the professionals, rather than casual advice from the street or the internet<\/li>\n<\/ul>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">The fear of withdrawal symptoms or the inability to resist the cravings to use again are major barriers to recovery. Medical detox directly addresses these problems and gives the individual a strong opportunity to succeed.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Some of the medications <a href=\"https:\/\/www.asam.org\/docs\/default-source\/practice-support\/guidelines-and-consensus-docs\/asam-national-practice-guideline-supplement.pdf\" target=\"_blank\" rel=\"noopener\">used in<\/a> medical detox include <a href=\"https:\/\/www.floridarehab.com\/treatment\/medication-assisted-treatment\/suboxone\/\">Suboxone<\/a>, <a href=\"https:\/\/www.floridarehab.com\/treatment\/medication-assisted-treatment\/methadone\/\">Methadone<\/a>, Lofexidine and Clonidine.<\/p>\n\n\n\n<h2 class=\" wp-block-heading eplus-wrapper\">Tapering Off Hydrocodone<\/h2>\n\n\n\n<h3 class=\" wp-block-heading eplus-wrapper\"><strong>How Long Does Hydrocodone Stay In Your System?<\/strong><\/h3>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Hydrocodone is available in both immediate-release and extended-release formulations. Hydrocodone is a short-acting opioid, and the time required to eliminate half of the drug (its half-life) ranges between 4 and 12 hours. The half-life for the immediate-release formulation of hydrocodone <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK537288\/\" target=\"_blank\" rel=\"noopener\">is<\/a> four hours, whereas the half-life for extended-release formulations ranges between 7 and 12 hours. Relative to opioids with a longer half-life, like methadone, the symptoms of hydrocodone withdrawal are more severe and last a shorter duration.<\/p>\n\n\n\n<h2 class=\" wp-block-heading eplus-wrapper\"><strong>Finding a Hydrocodone Detox Center<\/strong><\/h2>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Undergoing medically assisted detox at an accredited facility is the safest and most effective way to rid the body of hydrocodone and transition smoothly into treatment and recovery. At The Recovery Village, we offer a full continuum of care to help you stop hydrocodone and keep you off the drug for good. This means a seamless integration from detox, where we ease you off hydrocodone, to rehab. Our rehab options are tailored to suit your needs and include:<\/p>\n\n\n\n<ul class=\"eplus-wrapper wp-block-list\">\n<li class=\" eplus-wrapper\">Intensive inpatient rehab<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Residential rehab<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Partial hospitalization<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Intensive outpatient rehab<\/li>\n\n\n\n<li class=\" eplus-wrapper\">Outpatient rehab<\/li>\n<\/ul>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Our goal is to help you overcome hydrocodone, and we are with you every step of the way in your recovery journey. Contact us today to learn more.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hydrocodone is one of the most prescribed and most abused opioids in the United States. Nearly all the world\u2019s hydrocodone is used in the United States, and more than 30 million prescriptions involving hydrocodone were dispensed in 2020 alone. Hydrocodone is available on its own as a long-acting tablet both as a generic drug and [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":14604,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false},"categories":[19],"tags":[49],"class_list":["post-3493","blog","type-blog","status-publish","hentry","category-hydrocodone","tag-opioids"],"acf":{"written_by":2446,"enable_medically_and_up":["Yes"],"medically_reviewed_by":289,"medically_reviewed_content":"This article was reviewed by a medical professional to guarantee the delivery of accurate and up-to- date information. <a href=\"\/research\/\">View our research policy.<\/a>","up_to_date":"","page_first_published_date":"20221229","page_last_edit_date":"20231207","highlighted_description":"If you or a loved one is struggling with addiction, help is available. Speak with a Recovery Advocate by calling <a href=\"tel:8886480738\"><b>888-648-0738<\/b><\/a> now.","key_takeaways":"","source":{"source_label":"View Sources","source_content":"<span style=\"font-weight: 400;\">Cardia, Luigi; Calapai, Gioacchino; Quattrone, Domenico; et al. \u201c<\/span><a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fphar.2018.01122\/full\"><span style=\"font-weight: 400;\">Preclinical and Clinical Pharmacology of Hydrocodone for Chronic Pain: A Mini Review<\/span><\/a><span style=\"font-weight: 400;\">.\u201d Frontiers in Pharmacology, October 1, 2018. Accessed September 4, 2023.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Drug Enforcement Administration. \u201c<\/span><a href=\"https:\/\/www.deadiversion.usdoj.gov\/drug_chem_info\/hydrocodone.pdf\"><span style=\"font-weight: 400;\">Hydrocodone<\/span><\/a><span style=\"font-weight: 400;\">.\u201d October 2019. Accessed September 4, 2023.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">International Narcotics Control Board. \u201c<\/span><a href=\"https:\/\/www.incb.org\/documents\/Publications\/AnnualReports\/AR2022\/Annual_Report\/E_INCB_2022_1_eng.pdf\"><span style=\"font-weight: 400;\">Report of the International Narcotics Control Board for 2021<\/span><\/a><span style=\"font-weight: 400;\">.\u201d 2022. Accessed September 4, 2023.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">ClinCalc. \u201c<\/span><a href=\"https:\/\/clincalc.com\/DrugStats\/Drugs\/AcetaminophenHydrocodone\"><span style=\"font-weight: 400;\">Acetaminophen; Hydrocodone - Drug Usage Statistics<\/span><\/a><span style=\"font-weight: 400;\">.\u201d Accessed September 4, 2023.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Drugs.com. \u201c<\/span><a href=\"https:\/\/www.drugs.com\/monograph\/hydrocodone.html\"><span style=\"font-weight: 400;\">HYDROcodone Monograph for Professionals<\/span><\/a><span style=\"font-weight: 400;\">.\u201d April 19, 2023. Accessed September 4, 2023.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Hallare, Jericho &amp; Gerriets, Valerie. \"<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK554498\/\"><span style=\"font-weight: 400;\">Half Life<\/span><\/a><span style=\"font-weight: 400;\">.\" StatPearls, June 20, 2023. Accessed September 4, 2023.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">American Society of Addiction Medicine. \u201c<\/span><a href=\"https:\/\/sitefinitystorage.blob.core.windows.net\/sitefinity-production-blobs\/docs\/default-source\/guidelines\/npg-jam-supplement.pdf?sfvrsn=a00a52c2_2\"><span style=\"font-weight: 400;\">National Practice Guideline for the Treatment of Opioid Use Disorder<\/span><\/a><span style=\"font-weight: 400;\">.\u201d December 18, 2019. Accessed September 4, 2023.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Substance Abuse and Mental Health Services Administration. \u201c<\/span><a href=\"https:\/\/store.samhsa.gov\/sites\/default\/files\/d7\/priv\/sma10-4554.pdf\"><span style=\"font-weight: 400;\">Protracted Withdrawal<\/span><\/a><span style=\"font-weight: 400;\">.\u201d July 2010. Accessed September 4, 2023.<\/span>"},"staff_member_heading":"Authorship","staff_member":[{"staff_member_title":"Editor","select_staff_member":2446},{"staff_member_title":"Medical Reviewer","select_staff_member":289}],"insurance_label":""},"_links":{"self":[{"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/blog\/3493","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/blog"}],"about":[{"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/types\/blog"}],"author":[{"embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/comments?post=3493"}],"version-history":[{"count":0,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/blog\/3493\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/blog\/14604"}],"acf:post":[{"embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/staff\/289"},{"embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/staff\/2446"}],"wp:attachment":[{"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/media?parent=3493"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/categories?post=3493"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/tags?post=3493"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}