{"id":3530,"date":"2023-07-27T07:41:49","date_gmt":"2023-07-27T07:41:49","guid":{"rendered":"https:\/\/www.floridarehab.com\/?page_id=3530"},"modified":"2025-02-07T12:34:44","modified_gmt":"2025-02-07T12:34:44","slug":"ketamine-overdose","status":"publish","type":"blog","link":"https:\/\/www.floridarehab.com\/drugs\/ketamine\/ketamine-overdose\/","title":{"rendered":"Ketamine Overdose: Signs, Symptoms &amp; Treatment"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Ketamine overdose can be dangerous, especially when combined with other substances<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.floridarehab.com\/drugs\/ketamine\/\">Ketamine<\/a>&nbsp;is often legally used as an anesthetic in both humans and animals. However, because it can make a person feel relaxed and can cause hallucinations or the sensation of being outside one\u2019s body, it is also used to get high.&nbsp;<a href=\"https:\/\/www.floridarehab.com\/drugs\/ketamine\/addiction\/\">Ketamine<\/a>&nbsp;is commonly given out at parties, raves, and clubs. Nonetheless,&nbsp; people can overdose on ketamine, and the drug becomes more dangerous when taken with other substances.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Causes Of Ketamine Overdose<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The exact cause of ketamine overdose is&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541087\/\" target=\"_blank\" rel=\"noreferrer noopener\">not well known<\/a>. However, doctors know that ketamine impacts many chemicals and receptors in the brain. These effects&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541087\/\" target=\"_blank\" rel=\"noreferrer noopener\">include<\/a>:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Blocking receptors for glutamate, a chemical that stimulates the brain<\/li>\n\n\n\n<li>Increasing the levels of norepinephrine, dopamine, and serotonin in the brain<\/li>\n\n\n\n<li>Blocking sodium and potassium channels in the brain that allow brain cells to activate and communicate with each other<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Ketamine Overdose Symptoms<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">When someone starts to overdose on ketamine, it may be hard to distinguish the drug\u2019s expected effects from an overdose. Therefore, it is important to know the common effects of ketamine. When someone takes ketamine, the hallucinogenic effects often start&nbsp;<a href=\"https:\/\/www.dea.gov\/sites\/default\/files\/drug_of_abuse.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">within a few minutes<\/a>&nbsp;and last for up to&nbsp;<a href=\"https:\/\/www.dea.gov\/sites\/default\/files\/drug_of_abuse.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">60 minutes<\/a>. However, the exact effects may&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541087\/\" target=\"_blank\" rel=\"noreferrer noopener\">depend on the dose<\/a>&nbsp;taken. Some of the first symptoms to take effect&nbsp;<a href=\"https:\/\/www.dea.gov\/sites\/default\/files\/drug_of_abuse.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">include<\/a>:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Unresponsiveness<\/li>\n\n\n\n<li>Rapid eye movements<\/li>\n\n\n\n<li>Enlarged pupils<\/li>\n\n\n\n<li>Excess saliva<\/li>\n\n\n\n<li>Teary eyes<\/li>\n\n\n\n<li>Muscle stiffening<\/li>\n\n\n\n<li>Nausea<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">During overdose, these symptoms may&nbsp;<a href=\"https:\/\/www.dea.gov\/sites\/default\/files\/drug_of_abuse.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">worsen<\/a>. An overdose can occur&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541087\/\" target=\"_blank\" rel=\"noreferrer noopener\">regardless of how the person has taken ketamine<\/a>. However, symptoms may be&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541087\/\" target=\"_blank\" rel=\"noreferrer noopener\">linked<\/a>&nbsp;to too-rapid use of ketamine or mixing ketamine with other drugs. These symptoms&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541087\/\" target=\"_blank\" rel=\"noreferrer noopener\">include<\/a>:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Stupor<\/li>\n\n\n\n<li>Unconsciousness<\/li>\n\n\n\n<li>Slowed breathing<\/li>\n\n\n\n<li>Blood pressure changes<\/li>\n\n\n\n<li>Heart rate changes<\/li>\n\n\n\n<li>Seizure<\/li>\n<\/ul>\n\n\n\n\n\n<h2 class=\"wp-block-heading\">Risks Of Ketamine Overdose<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Although a ketamine overdose itself is rarely lethal, it can be very dangerous when used with other substances. The risk of overdose from ketamine&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2443940\/\" target=\"_blank\" rel=\"noreferrer noopener\">can increase<\/a>&nbsp;when more than one substance is used. This occurs because multi-substance use can cause the drugs to have an additive effect in the body. This is often the case as&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2443940\/\" target=\"_blank\" rel=\"noreferrer noopener\">one study<\/a>&nbsp;showed that among people who regularly take ketamine:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Almost 90% had used&nbsp;<a href=\"https:\/\/www.floridarehab.com\/alcohol\/addiction\/\">alcohol<\/a>&nbsp;in the past 30 days<\/li>\n\n\n\n<li>Nearly 81% had used&nbsp;<a href=\"https:\/\/www.floridarehab.com\/drugs\/marijuana\/addiction\/\">cannabis<\/a>&nbsp;in the past 30 days<\/li>\n\n\n\n<li>Close to 45% had taken&nbsp;<a href=\"https:\/\/www.floridarehab.com\/drugs\/heroin\/\">heroin<\/a>&nbsp;in the past 30 days<\/li>\n\n\n\n<li>Around 40% had taken&nbsp;<a href=\"https:\/\/www.floridarehab.com\/drugs\/cocaine\/addiction\/\">cocaine<\/a>&nbsp;or&nbsp;<a href=\"https:\/\/www.floridarehab.com\/drugs\/crack\/\">crack<\/a>&nbsp;in the past 30 days<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">However, even when used alone, ketamine can be dangerous. A major risk of ketamine overdose is medical complications. These can&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541087\/\" target=\"_blank\" rel=\"noreferrer noopener\">include<\/a>:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Rhabdomyolysis, a condition where muscles are damaged and their contents are released into the blood<\/li>\n\n\n\n<li>Seizures<\/li>\n\n\n\n<li>Ongoing psychiatric disturbances, like&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541087\/\" target=\"_blank\" rel=\"noreferrer noopener\">problems<\/a>&nbsp;with memory, concentration, sleep, and mood<\/li>\n\n\n\n<li>Chronic ulcerative cystitis, a condition where ulcers painfully inflame the bladder<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Avoiding An Overdose<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The best way to avoid a ketamine overdose is to not take ketamine. However, if someone is going to take ketamine, it is best to encourage them to not use other drugs along with it. This is especially true for other substances that can slow breathing like:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Opioids<\/li>\n\n\n\n<li>Benzodiazepines<\/li>\n\n\n\n<li>Alcohol<\/li>\n<\/ul>\n\n\n\n\n\n<h2 class=\"wp-block-heading\">Treatment for Ketamine Overdose<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">If someone starts to overdose on ketamine, it is important to seek emergency medical attention right away. An overdose can be very dangerous, especially if the person took ketamine with other substances. A doctor will often perform additional tests on the person&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541087\/\" target=\"_blank\" rel=\"noreferrer noopener\">like<\/a>:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Blood tests to see if the person is overdosing on any other substances<\/li>\n\n\n\n<li>A heart test to rule out complications from ketamine overdose like heart problems<\/li>\n\n\n\n<li>Urine tests to make sure the person is not having a complication from ketamine overdose like rhabdomyolysis<\/li>\n\n\n\n<li>A brain scan to rule out any trauma or hemorrhage, because people taking ketamine are at higher risk of&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541087\/\" target=\"_blank\" rel=\"noreferrer noopener\">accidents<\/a><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">In most cases, ketamine overdose does&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541087\/\" target=\"_blank\" rel=\"noreferrer noopener\">not require<\/a>&nbsp;specific treatment. However, medications can manage specific overdose symptoms like blood pressure changes. It is important for doctors to monitor the person who is overdosing because complications like breathing problems and heart problems can be serious. In many cases, patients who overdosed on ketamine can go home a&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541087\/\" target=\"_blank\" rel=\"noreferrer noopener\">few hours<\/a>&nbsp;after their symptoms improve. However, someone who has overdosed on ketamine may need additional&nbsp;<a href=\"https:\/\/www.floridarehab.com\/treatment\/\">treatment for an addiction<\/a>. In this case, an addiction recovery center may be able to help.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>If you or someone you love is struggling with ketamine use, we can help.&nbsp;<a href=\"https:\/\/www.floridarehab.com\/contact-us\/\">Contact<\/a>&nbsp;our trained professionals at The Recovery Village Palm Beach at Baptist Health to learn how we can help you live a ketamine-free life. Don\u2019t wait; call us today.<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ketamine overdose can be dangerous, especially when combined with other substances Ketamine&nbsp;is often legally used as an anesthetic in both humans and animals. However, because it can make a person feel relaxed and can cause hallucinations or the sensation of being outside one\u2019s body, it is also used to get high.&nbsp;Ketamine&nbsp;is commonly given out at [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":3524,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false},"categories":[87],"tags":[],"class_list":["post-3530","blog","type-blog","status-publish","hentry","category-ketamine"],"acf":{"written_by":319,"enable_medically_and_up":["Yes"],"medically_reviewed_by":289,"medically_reviewed_content":"This article was reviewed by a medical professional to guarantee the delivery of accurate and up-to- date information. <a href=\"\/research\/\">View our research policy.<\/a>","up_to_date":"<i>Last Updated<\/i> - <b>12\/29\/2022<\/b>","page_first_published_date":"20221229","page_last_edit_date":"20221229","highlighted_description":"If you or a loved one is struggling with addiction, help is available. Speak with a Recovery Advocate by calling <a href=\"tel:8886480738\"><b>888-648-0738<\/b><\/a> now.","key_takeaways":"","source":{"source_label":"View Sources","source_content":"Lankenau, Stephen E; et al. \u201c<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2443940\/\" target=\"_blank\" rel=\"noopener\">Prevalence and Patterns of Prescription Drug Misuse among Young Ketamine Injectors<\/a>.\u201d Journal of Drug Issues, 2007. Accessed November 9, 2019.\r\n\r\nU.S. Department of Justice, Drug Enforcement Administration. \u201c<a href=\"https:\/\/www.dea.gov\/sites\/default\/files\/drug_of_abuse.pdf\" target=\"_blank\" rel=\"noopener\">Drugs of Abuse<\/a>.\u201d 2017. Accessed November 9, 2019.\r\n\r\nOrhurhu, Vwaire J.; Claus, Lauren E.; Cohen, Steven P. \u201c<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541087\/\" target=\"_blank\" rel=\"noopener\">Ketamine Toxicity<\/a>.\u201d StatPearls, April 11, 2019. Accessed November 9, 2019."},"staff_member_heading":"Authorship","staff_member":[{"staff_member_title":"Editor","select_staff_member":319},{"staff_member_title":"Medical Reviewer","select_staff_member":289}],"insurance_label":""},"_links":{"self":[{"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/blog\/3530","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/blog"}],"about":[{"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/types\/blog"}],"author":[{"embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/comments?post=3530"}],"version-history":[{"count":0,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/blog\/3530\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/blog\/3524"}],"acf:post":[{"embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/staff\/289"},{"embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/staff\/319"}],"wp:attachment":[{"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/media?parent=3530"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/categories?post=3530"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.floridarehab.com\/wp-json\/wp\/v2\/tags?post=3530"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}